Here’s another short animation I worked on for Al Jazeera’s medical show ‘The Cure’.

After witnessing a cholera outbreak in what is now Bangladesh in the 1960s, David Nalin helped to develop an oral rehydration therapy which has saved the lives of over 50 million people.

In emergency situations, Nalin noted that the traditional cholera treatment of intravenously hydrating patients was prohibitively slow and expensive.

Instead, Nalin researched oral rehydration and realised that each cholera patient needed to be given the same amount of rehydration fluid as they had lost due to diarrhoea.

By mixing potassium chloride, sodium chloride, sodium bicarbonate and glucose into water and giving each patient as many litres as they were lacking, Nalin and his team demonstrated, for the first time, a 70-80 percent reduction in the amount of intravenous fluid needed to save cholera sufferers.

The simple solution was easy to administer and revolutionised the treatment for diarrhoeal disease.

The prestigious medical journal The Lancet described David Nalin and his team’s findings as “potentially the most important medical advance of this century.” In this animation for The Cure, we mark Nalin’s pioneering work in the world of medicine.

If  you enjoyed that, you can see the full show  here:  http://www.aljazeera.com/programmes/thecure/

If you’re interested in more unsung heroes from the medical world, check out these two animations on Henrietta Lacks, Charles Drew and Henry Molaison.

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New pharmaceuticals can help combat the deadly disease, but delivering it to the people in need remains an obstacle.

by Arwa Aburawa

As the narrow, hollowed out canoe glides up the River Uele in the Democratic Republic of Congo, Dr Javid Abdelmoneim gestures to the surrounding wilderness and says “sleeping sickness affects people this isolated, people this poor”. And this, in sum, is the challenge facing those attempting to eradicate the deadly disease which leads to serious brain damage, disrupted sleep patterns and eventually death.

A parasitic infection that poses a risk to 70 million people across 36 sub-Saharan African countries, sleeping sickness has been declared a “neglected” tropical disease by the World Health Organisation (WHO). The organisation assigns this classification to various diseases where no significant treatment has been developed for decades. “Why are they neglected?” asks Abdelmoneim. “The cold light of truth is they are neglected because poor people are affected.”

In the case of sleeping sickness, which is also known as human African trypanosomiasis, the last significant medical breakthrough occurred in 1949. That was until Medecins Sans Frontieres (MSF), the international medical aid organisation, funded the Drugs for Neglected Diseases Initiative (DNDI) to help eliminate the infection. In 2009, DNDI delivered a new treatment which combined two drugs, nifurtimox and eflornithine, offering real hope that the parasitic disease would be eliminated as a health problem by 2020. The combined drugs provide an alternative to the previous arsenic-derived medication, melarsoprol. It is estimated that one in 20 patients were killed by the toxic treatment.

This development, however, is only part of the solution – the real challenge is delivering it to the people who need it most. “We don’t have a clue how many are living on the river. They are really, really remote,” explains Marie Cleret from MSF. “It’s not even villages, sometimes it’s just a few people living on the banks of the river.” It’s these people that MSF’s Democratic Republic of Congo (DRC) team are hoping to screen for the disease. Although deadly in the later stages, a person can be infected for months – even years – without displaying any major symptoms. By the time the disease kicks into the second phase, where parasites cross the blood-brain barrier and attack the central nervous system, it is harder to treat.

In Bunia, in north-eastern DRC, MSF’s mobile sleeping sickness teams prepare supplies and co-ordinate their movements which often take them between planes and motorbikes to canoes to reach far flung communities. With more than 85 percent of all reported cases occurring in the former Belgian colony, MSF launched an extensive campaign to screen those living in the most remote communities of the country. In 2012, they screened 60,000 people and treated more than 1,000 for the disease.

The team’s next journey is to Nekpotolia, a fishing village on an island in the middle of the River Uele, as the waterway snakes its way through the north of the DRC. Tables and chairs are loaded onto the canoes – alongside refrigerators keeping medical equipment between 2°C and 8°C.

MSF first visited Nekpotolia around six months ago, and found a sleeping sickness prevalence of 3.57 percent. Anything higher than one percent is considered an epidemic. This time they find another positive case of sleeping sickness. “Jean Pierre’s now got to have a lumbar puncture to stage the disease,” said Abdelmoneim. “We’ve got to get fluid from his spine so we know at what stage the disease is, how severe it is.”

Following the painful procedure – performed without anaesthetic – Jean Pierre is found to be a stage one patient, meaning he can be treated onsite. Another patient in the village of Kayibi wasn’t so lucky. Winston was diagnosed with stage two sleeping sickness and joined the MSF team for the ride back to the town of Dingila to undergo a treatment programme.

In developed cases of sleeping sickness such as Winston’s, the patient receives an intravenous infusion, twice a day, every day for ten days. The infusions, which come in heavy glass bottles, must be administered by a nurse or doctor restricting treatment to only those who have access to a hospital.

The latest development in the treatment of the disease is a drug, fexinidazole, currently being clinically trialed by MSF. The drug comes in tablet form, it’s light, it’s easy to administer and could be another step towards eradicating the disease. Although still in the early stages, if successful, “fexi” could be used to treat both stage one and two patients – which would simplify the treatment regimen. Dr Michel Sambili, an MSF doctor working on the trial, is optimistic. “With fexi, we will resolve above all the logistical headache,” he says. “It will solve lots of problems – especially for the poor population.”

In 1995, the WHO estimated the number of sleeping sickness cases at more than 300,000. Today the number of cases is just 10 percent of that. “When you think about where we were years ago and the situation we have now in the DRC, it’s clear we’ve made lots of progress,” remarks Jeroen Beijnsberger, an MSF coordinator.

“Yes, we still have a lot of work left, in terms of simplification of diagnosis and treatment – and monitoring will always be important – but I think the goal of elimination by 2020 is certainly attainable.”

Follow Arwa Aburawa on Twitter: @arwa_journalist

Originally published on the Al Jazeera English website here: http://www.aljazeera.com/indepth/features/2013/09/2013913123554765598.html

Here’s a little animation on an unsung medical hero which I worked on for Al Jazeera’s medical show – see below.

It is 1847 and the death rate among pregnant women in the Viennese obstetric clinics where the  physician Ignaz Semmelweis works is high. Puerperal fever, which is an infection of the female reproductive organs following childbirth, is a common cause of death and is almost seen as inevitable by medics at the time.

However, a worrying trend in the clinics which Semmelweis supervises in Vienna catches his eye.

After dealing with women so desperate to avoid one clinic that they would rather give birth in the street, Semmelweis decided to look into mortality rates.

He found that the student-run clinic had a much higher mortality rate from puerperal fever than the clinic run by midwives; sometimes three times higher.

Semmelweis came to the conclusion that the students carried something from the mortuary where they carried out autopsies, to the women they later examined. He ordered the students to wash their hands with chlorinated lime solution before every examination. Almost immediately, the mortality rate fell from 18 percent to one percent.

Despite the successful hand-washing policy, Semmelweis could offer no acceptable medical explanation for its effectiveness. The idea that germs exist and cause infections was not developed at the time.

After struggling for years to promote his hand disinfection policies, Semmelweis was admitted to an insane asylum at the age of 47, and he died 14 days later.

In this animation for The Cure, we explore Semmelweis’s ground-breaking contribution to the field of medical hygiene.

Hat tip to Marc Hudson. 

Here’s a very sneaky peek of my article on the environmental  and also human rights implications of throwaway fashion. I wrote the article for Aquila Style Magazine in the wake of the Rana Plaza factory collapse in Bangladesh which left over a 1,000 people (mostly Muslim women) dead. To read the full article, download the online magazine for a couple of dollars here.

Here’s my latest piece for DW. It’s actually a collaboration with another journalist – Vanessa O’Brien who helped with the audio to accompany the online article. Check out the audio piece here: Jordan expands its nuclear plans.

As Jordan works on plans to build its first nuclear plant, protestors are still criticizing the country’s decision to go nuclear in the first place. They say it wastes water and ignores the nation’s renewables potential.